Perbandingan Antara Fentanil 2 μg/kgBB/jam dan Scalp Block Terhadap Peningkatan Hemodinamik dan Kadar Glukosa Darah Sewaktu Saat Pemasangan Pin Kepala Pada Kraniotomi

Robert Sihombing, Dewi Yulianti Bisri, Ruli Herman Sitanggang

Abstract


Latar Belakang dan Tujuan: Opioid dosis tinggi efektif memblokade nyeri pada operasi kraniotomi namun memiliki efek yang tidak diinginkan. Alternatif lain menggunakan teknik scalp block dikombinasikan dengan anestesi umum. Tujuan penelitian ini untuk membandingkan hemodinamik dan kadar glukosa darah sewaktu (GDS) antara fentanil 2 μg/kgBB/jam dan scalp block saat pemasangan pin kepala pada kraniotomi pengangkatan tumor elektif dengan anestesi umum.

Subjek dan Metode: Penelitian ini dilakukan pada 28 pasien yang direncanakan pembedahan tumor otak elektif. Subjek penelitian dibagi menjadi dua kelompok: scalp block dan kelompok fentanil 2 μg/kgBB/jam. Tekanan arteri rerata, laju nadi dan kadar GDS intraoperatif dinilai dan dianalisis menggunakan uji-t berpasangan dan Chi-square.

Hasil: MAP dan laju nadi antara kedua grup memiliki perbedaan signifikan (p<0,05). Kelompok fentanil memiliki MAP dan laju nadi lebih tinggi dibanding dengan kelompok scalp block. Namun perbandingan kadar GDS antara kedua kelompok tidak menunjukkan hasil yang signifikan (p>0,05).

Simpulan: Scalp block lebih efektif dalam mengurangi peningkatan hemodinamik namun sama efektif dengan fentanil 2 μg/kgBB/jam dalam mengurangi peningkatan kadar GDS pada pasien yang menjalani operasi kraniotomi pengangkatan tumor elektif.


Comparison Between Fentanyl 2 μg/kg/hr and Scalp Block of Hemodynamic Improvement and Blood Glucose Levels During Head Pin Installment in Craniotomy


Background and Objective: High dose opioids is one of the most effective techniques for blocking pain in craniotomy surgery but it has undesirable effect. Other alternative to overcome pain in craniotomy is using a scalp block technique in combination with general anesthesia. The aim of this study was to compare the increase of hemodynamic and blood glucose levels (BGL) between fentanyl 2 μg/kgBW/hr and scalp block during head pin installment in craniotomy surgery.

Subject and Method: Twenty eight patients undergoing elective craniotomy tumor removal surgery were enrolled in the study. The patients were divided into two groups: scalp block and fentanyl 2 μg/kgBW/hr. Intraoperative mean arterial pressure (MAP), heart rate (HR) and BGL were recorded, and analyzed by paired t-test and Chisquare.

Result: MAP and HR showed significant differences between groups (p<0,05), wherein fentanyl group had higher MAP and HR than scalp block group. However, BGL during head pin installment did not show significant results between the two groups (p> 0,05).

Conclusion: Scalp block is more effective than fentanyl 2 μg/kgBW/hr in reducing increased of hemodynamic but equally effective with fentanyl in reducing increased of BGL during head pin installment in craniotomy tumor removal.


Keywords


Fentanil, glukosa darah sewaktu; laju nadi; scalp block; tekanan arteri rerata; Blood glucose levels; fentanyl; heart rate; mean arterial pressure; scalp block

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DOI: https://doi.org/10.24244/jni.vol7i2.5

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