Tatalaksana Cerebral Venous Sinus Thrombosis dengan Alkoholik dan Perdarahan Intraserebral
Abstract
Cerebral venous sinus thrombosis (CVST) adalah suatu sindrom seperti stroke, angka kejadiannya sangat jarang, sehingga dapat menjadi dilema bagi dokter di instalasi gawat darurat dalam menegakkan diagnosis. Seorang lelaki 25 tahun, 50 kg, tinggi badan 165 cm, mengeluh lemah anggota badan sebelah kanan sejak 12 jam sebelum masuk rumah sakit. Keluhan disertai dengan sukar berbicara. Satu hari sebelum masuk rumah sakit, pasien mabuk-mabukan dan mengalami muntah-muntah ± 3–5 x/hari. Riwayat kejang, konsumsi obat-obatan dan trauma sebelumnya disangkal. Tidak ada riwayat demam, hipertensi, diabetes mellitus dan penyakit penyerta lainnya. Dilakukan dekompresi evakuasi perdarahan sebagai tindakan penyelamatan jiwa setelah pasien terehidrasi, operasi dilakukan dalam anestesi umum. Lama operasi selama 2 jam dan lama pasien teranestesi 2 jam 15 menit. Pasien dirawat di ICU selama 2 hari, lalu dipindahkan ke ruang HCU. Pada hari ke-5 pascabedah mulai diberikan enoxaparin sodium 50 mg subcutan selama 6 hari. Lalu pasien dipindahkan ke ruang rawat inap dan pulang ke rumah pada hari ke-15 perawatan. Target pencapaian utama pada pasien CVST adalah untuk rekanalisasi penyumbatan, menjaga venous return, mengurangi risiko hipertensi vena, infark serebral dan emboli paru. Algoritma tatalaksana pasien CVST terkadang harus disesuaikan dengan kondisi klinis pasien saat tiba di rumah sakit. Pemberian low-weightmoleculer heparin (LWMH) tetap diberikan selama tidak terjadi peningkatan tekanan darah yang bermakna
Cerebral Venous Sinus Thrombosis Management with Alkoholic and Intracerebral Hemorrhage
Cerebral venous sinus thrombosis (CVST) is a syndrome similar a stroke, the incidence is very rare, so it can be a dilemma for doctors at emergency departments to make the diagnosis. A 25 year old male weighing 50 kg and height 165 cm. Patients complained of right limb wekness since 12 hours before admission. Complaints are accompanied by difficulty speaking. One day before entering the hospital, the patient got drunk and experienced vomiting ± 3–5 times a day. History of seizures, previous consumption of drugs and trauma was denied. No history of fever, hypertension, diabetes mellitus and other comorbidities. Decompression by hematoma evacuation was performed as a life-saving action after the patient was hydrated, surgery was performed under general anesthesia. Operation duration was 2 hours and anesthesia duration was 2 hours 15 minutes. The patient was admitted to the ICU for 2 days, then transferred to the HCU room. On the 5th day post-surgery patient got 50 mg subcutaneous enoxaparin for 6 days. Then the patient was transferred to the ward and returned home on the 15th day of treatment. The main achievement targets in CVST patients were for clotting recanalization, maintaining venous return, reducing the risk of venous hypertension, cerebral infarction and pulmonary embolism. The CVST patient management algorithm sometimes has to be adjusted to the patient's clinical condition upon arrival at the hospital. Provision of LWMH is still given as long as the blood pressure does not increase significantly.
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Algahtani HA, Aldarmahi AA. Cerebral venous sinus thrombosis. Neurosciences (Riyadh) 2014; 19: 11-16.
Bousser MG, Ferro JM. Cerebral venous thrombosis: an update. Lancet Neurol 2007; 6: 162-170.
Stam J. Thrombosis of the cerebral veins and sinuses. N Engl J Med 2005; 352: 1791-8.
Fischer C, Goldstein J, Edlow J. Cerebral venous sinus thrombosis in the emergency department: retrospective analysis of 17 cases and review of the literature. J Emerg Med 2010; 38: 140-47.
Guenther G, Arauz A. Cerebral venous thrombosis: a diagnostic and treatment update. Neurologia 2011; 26: 488-98.
Oppenheim C, Domigo V, Gauvrit JY, Lamy C, Mackowiak-Cordoliani MA, Pruvo JP, et al. Subarachnoid hemorrhage as the initial presentation of dural sinus thrombosis. AJNR Am J Neuroradiol 2005; 26: 614-17.
Boukobza M, Crassard I, Bousser MG, Chabriat H. Radiological findings in cerebral venous thrombosis presenting as subarachnoid hemorrhage: a series of 22 cases. Neuroradiology 2016; 58: 11-6.
Gu J, Li B, Chen J, Hong J, Liu H, Wang S. Cerebral venous thrombosis and acute subarachnoid hemorrhage: a retrospective study on diagnosis, treatment prognosis of 11 patients. Biomedres 2017; 28 (19): 8496-50
Singh H, Paulomi T, Ray S, Gupta V. A rare presentation of acute alcohol intoxication, subarachnoid haemorrhage and cortical venous thrombosis. J Neurol Res 2012;2:62-4.
Canhao P, Bousseur MG, Barinagarrementeria F, Stam J, Ferro JM; The ISCVT Collaborators. Predisposing conditions for cerebral vein and dural sinus thrombosis. Available from: http://www.iscvt.com/index.htm. [Last cited on 2013 Dec 20].
Ntaios G, Bornstein NM, Caso V, et al. The European Stroke Organisation Guidelines: a standard operating procedure. Int J Stroke 2015; 10: 128–35
Ferro JM, BousserM.-G., Canhão P, Coutinho JM, Cassard I, Dentali F, dkk. European Stroke Organization guideline for the diagnosis and treatment of cerebral venous thrombosis - endorsed by the European Academy of Neurology. European Stroke Journal 2017; 2 (3): 195-221
Einh äupl K, Stam J, Bousser MG, et al. EFNS guideline on the treatment of cerebral venous and sinus thrombosis in adult patients. Eur J Neurol 2010; 17: 1229–235.
Saposnik G, Barinagarrementeria F, Brown RD Jr, et al. Diagnosis and management of cerebral venous thrombosis: a statement for healthcare professionals from the American Heart Association/American Stroke Association. Stroke 2011; 42: 1158–92.
Coutinho JM. Cerebral venous Thrombosis. J Thromb Haemost 2015; 13 (1): S238-S44.
Coutinho JM, Middeldrop S, Stam J. Advaces in the treatment of cerebral venous thrombosis. Curr Treat Options Neuro I 2014; 16: 299-310.
Bisri T. Penanganan neuroanesthesia dan critical care: cedera otak traumatik. Bandung: Universitas Padjadjaran; 2012.
Saleh SC. Cairan untuk tindakan bedah otak. Dalam: Saleh SC, editor. Sinopsis Neuroanestesia Klinik, edisi ke-2, Surabaya: Zifatama; 2013, 49-60.
Wlody DJ, Weems L. Anesthesia for neurosurgery in the pregnant patient. Dalam: Cottrell JE, Young WL, editor. Cottrell and Young’s Neuroanesthesia, edisi ke-5, Philadelphia: Mosby; 2010, 416-24
DOI: https://doi.org/10.24244/jni.vol7i1.30
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